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Unusual presentation of pemphigus vulgaris
Author(s) -
Bardazzi Federico,
Guerra Liliana,
Peluso Anna Maria,
Piraccini Bianca Maria,
Morelli Rossella
Publication year - 1994
Publication title -
journal of the european academy of dermatology and venereology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 107
eISSN - 1468-3083
pISSN - 0926-9959
DOI - 10.1111/j.1468-3083.1994.tb00076.x
Subject(s) - pemphigus vulgaris , acantholysis , medicine , dermatology , paronychia , pemphigus , conjunctiva , pathology , presentation (obstetrics) , biopsy , autoantibody , antibody , immunology , surgery
We report a case of a 50‐year‐old man who presented with a conjunctival erosion and lesions resembling acute paronychia of several fingers. The Tzanck preparation from the conjunctiva showed the presence of acantholytic cells. Skin biopsy showed suprabasal cleft formation with acantholysis. Direct immunofluorescence revealed intercellular epidermal staining with IgG and C3. Diagnosis of pemphigus vulgaris was therefore confirmed. Nail abnormalities that can be observed in pemphigus vulgaris are discussed.