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Evaluation of antimicrobial effectiveness of C‐8 xylitol monoester as an alternative preservative for cosmetic products
Author(s) -
Amaral L. F. B.,
Camilo N. S.,
Pereda M. D. C. V.,
Levy C. E.,
Moriel P.,
Mazzola P. G.
Publication year - 2011
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1468-2494.2010.00633.x
Subject(s) - xylitol , preservative , antimicrobial , cosmetics , food science , chemistry , traditional medicine , medicine , organic chemistry , fermentation
Synopsis Xylitol is a natural sugar derived from plants, fruits and vegetables, whose antimicrobial properties are described in the literature. This study aimed to evaluate the antimicrobial effectiveness of C‐8 xylitol monoester, for its use as a preservative in cosmetic formulations. The minimum inhibitory concentration (MIC) was determined by the broth macrodilution method, and the antimicrobial effectiveness of C‐8 xylitol monoester was determined by using challenge test method. The results obtained in the determination of minimum inhibitory concentration are between 1.0% and 1.25% for Staphylococcus aureus , Escherichia coli and Candida albicans and between 1.0% and 1.5% for Pseudomonas aeruginosa and Aspergillus niger . The amount of 1% of C‐8 xylitol monoester was added to the lotion used in the challenge test, observing a rapid decline in the number of CFU g −1 in stages of evaluation after contamination of the product by all bacteria. The same occurs in relation to C. albicans , which shows a 90% reduction in the number of CFU g −1 . Regarding A. niger , similar reduction is observed when pH value of the lotion is adjusted from 5.5 to 7.0. The results indicate that under the tests conditions, C‐8 xylitol monoester has antimicrobial activity and could be considered as an alternative preservative for cosmetic formulations.