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Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis
Author(s) -
XhauflaireUhoda E.,
Henry F.,
PiérardFranchimont C.,
Piérard G. E.
Publication year - 2009
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1468-2494.2009.00505.x
Subject(s) - diaper dermatitis , zinc , dermatology , medicine , chemistry , organic chemistry
Synopsis Diaper dermatitis affects nearly 50% of infants as well as some bed‐ridden adults particularly in the elderly people. This condition is induced by irritation and maceration, and may be further exacerbated by Candida sp. colonization and infection. A key factor in the pathogenesis is the alteration in both the barrier function and the water‐holding capacity of the stratum corneum. The purpose of this study was to assess the effects of an unmedicated zinc oxide–petrolatum paste and to observe for possible shielding and restoring effects on the water‐holding capacity of the stratum corneum altered by diaper dermatitis. The paste appeared to load the hollow skin microrelief. It was inferred that this effect was responsible for a reticulated shielding effect. Compared with healthy skin and untreated diaper dermatitis, the application of the anhydrous paste resulted in a trend to normalize electrometric properties of skin reflecting the combination of transepidermal water loss and the water‐holding capacity of the stratum corneum.