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Vol.42, No.1, pp.36‐39, 2008
Determination of diethylene glycol in toothpaste
Author(s) -
Kamimura M.,
Mizuno K.,
Kuromi K.,
Ueno C.,
Kurita H.,
Owada K.,
Yamamoto M.
Publication year - 2009
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1468-2494.2008.00450_6.x
Subject(s) - toothpaste , diethylene glycol , chromatography , methanol , gas chromatography , chemistry , detection limit , cosmetics , ethylene glycol , organic chemistry
A rapid and simple method using gas chromatography (GC) for the determination of diethylene glycol (DEG) in toothpaste was developed. DEG in toothpaste was extracted with methanol containing 1,4‐butanediol as the internal standard by using an ultrasonic bath. The centrifuged and filtrated methanol extracts were analyzed by GC on an InertCap 624 capillary column. The recoveries of DEG from toothpaste fortified at the levels of 0.1, 0.5 and 1.0%, were 103.6, 99.9, 99.4%, respectively. The quantitation limit of DEG in toothpaste was 0.05??%. The proposed method could be applied to other cosmetics on the market without any interference. By using this method, DEG was detected the presence in two out of 10 toothpaste samples set to the hotel. This analytical method should be useful for quality control for manufacturers and importers of cosmetics. Keywords: diethylene glycol (DEG), toothpaste, gas chromatography, capillary column, 1,4‐butanediol, methanol extract, cosmetics, determination, analysis, DEG detection