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Green procedure for the preparation of scented alcohols from carbonyl compounds
Author(s) -
Villa Carla,
Trucchi Beatrice,
Gambaro Raffaella,
Baldassari Sara
Publication year - 2008
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1468-2494.2008.00431.x
Subject(s) - sodium borohydride , chemistry , cinnamyl alcohol , organic chemistry , alcohol , context (archaeology) , green chemistry , solvent , alcohol oxidation , ethanol , carbonyl group , catalysis , medicinal chemistry , reaction mechanism , cinnamaldehyde , paleontology , biology
Synopsis Several alcohols – interesting as cosmetic fragrances whose main preparative route on an industrial scale or in the research laboratory is the reduction of the corresponding carbonyl compound – were obtained by a solvent‐free methodology in a green chemistry context. The process involves the simple mixing of the carbonyl compound with sodium borohydride dispersed in wet alumina in the solid state; the conversions of the carbonyl compounds were obtained in good yields within short reaction times, without energy consumption. The following carbinols were studied: octan‐3‐ol, 2‐cineolylols ( endo–exo mixture), α‐ionol, 4‐methylbenzyl alcohol, 1‐phenylethanol, trans‐ cinnamyl alcohol, p‐ anisyl alcohol, 4‐phenyl‐3‐buten‐2‐ol.