Premium
Estimating the lifetime economic burden of P arkinson's disease in S ingapore
Author(s) -
Zhao Y. J.,
Tan L. C. S.,
Au W. L.,
Heng D. M. K.,
Soh I. A. L.,
Li S. C.,
Luo N.,
Wee H. L.
Publication year - 2013
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2012.03868.x
Subject(s) - medicine , purchasing power parity , total cost , cohort , indirect costs , demography , disease burden , emergency medicine , disease , pediatrics , finance , business , accounting , sociology , exchange rate , economics , microeconomics
Background and purpose We aimed to estimate the lifetime cost of P arkinson's disease ( PD ) from the societal perspective. Methods A convenience sample of E nglish or C hinese‐speaking patients with PD was recruited from a PD and M ovement D isorders C entre in S ingapore to complete a financial burden questionnaire. Sociodemographic and clinical data were retrieved from hospital databases. Markov cohort model analysis was performed (cycle length, 1‐year; duration, death or reached 100 years old). Patients were assumed to progress from one M arkov state to the next state or death without skipping states or regressing. All model parameters were based on published local data. Results In 195 patients with PD (median age: 68.9, male: 51.8%), the simulated lifetime cost of PD was S ingapore D ollar ( SGD ) 60 487 ( EUR purchasing power parity 56 253) per patient. Direct medical, non‐medical and indirect cost accounted for 18.8%, 12.8% and 68.4% of total lifetime cost, respectively. The top three components of total lifetime cost were productivity losses (67.6%), pharmacotherapy (11.4%) and home care (8.7%). One‐way sensitivity analysis and probabilistic sensitivity analyses revealed that estimates were sensitive to cost at H & Y stage 1, 2 and 2.5 and productivity losses. Conclusions The lifetime cost of PD is evaluated for the first time. This cost is substantial and comparable to the lifetime cost of intracerebral haemorrhage in at least one study. Our study identified several priority areas for research and policy formulation: reducing productivity losses, reducing cost of pharmacotherapy, avoiding hospitalization and reducing home care cost.