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Sex differences in perihemorrhagic edema evolution after spontaneous intracerebral hemorrhage
Author(s) -
Wagner I.,
Volbers B.,
Kloska S.,
Doerfler A.,
Schwab S.,
Staykov D.
Publication year - 2012
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2011.03628.x
Subject(s) - medicine , intracerebral hemorrhage , spontaneous intracerebral hemorrhage , edema , brain edema , anesthesia , subarachnoid hemorrhage
Background and purpose: Clinical data on sex differences in perihemorrhagic edema (PHE) after intracerebral hemorrhage (ICH) are lacking. Methods: Patients with spontaneous supratentorial ICH who had received standard conservative treatment were identified retrospectively. PHE development was assessed over a 14‐day period on follow‐up CT scans (days 1, 2–4, 5–7, 8–11, and 12–14). ICH and PHE volumes were assessed semiautomatically and compared between men and women. Results: A total of 387 patients (233 men) were included. Starting at days 2–4, women showed lower PHE values ( P < 0.05; days 2–4, 8–11) or a trend toward significance ( P ≤ 0.1; days 5–7, 12–14). Conclusions: Female sex may predict lower PHE volumes.