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Moving forward with nutrition in Alzheimer’s disease
Author(s) -
Scheltens P.
Publication year - 2009
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2009.02738.x
Subject(s) - medicine , disease , randomized controlled trial , clinical trial , intensive care medicine , cognition , intervention (counseling) , gerontology , pediatrics , psychiatry
Alzheimer’s disease (AD) is the epidemic of the 21st century but still relatively little is known about the causes of the disease. Nutrient deficiencies, associated with loss of cognitive function, are frequently reported in patients with AD and currently available epidemiologic evidence suggests that an increased intake of certain nutrients may lower the risk of AD. Current treatment options offer only symptomatic relief, however, there is a growing body of evidence that nutrition in general and ‘nutritional intervention’ in a clinical setting may be able to play a key role in the management of the disease. However, randomized clinical trials are needed to test this approach. The Souvenir study is the first randomized, controlled, double‐blind, multi‐centre study designed to evaluate the efficacy of a multi‐nutrient dietary approach on cognitive performance in drug‐naïve early AD patients.