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Total daily sleep duration and the risk of dementia: a prospective population‐based study
Author(s) -
BenitoLeón J.,
BermejoPareja F.,
Vega S.,
Louis E. D.
Publication year - 2009
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2009.02618.x
Subject(s) - medicine , dementia , confounding , population , sleep (system call) , prospective cohort study , duration (music) , relative risk , confidence interval , demography , disease , sociology , art , literature , environmental health , computer science , operating system
Background and purpose: We determined in a population‐based study whether sleep duration was associated with an increased risk of incident dementia. Methods: In a population‐based study in central Spain, participants were evaluated at baseline and 3 years later. Baseline demographic variables were recorded and participants indicated their daily sleep duration as the sum of night‐time sleep and daytime napping. The average daily total sleep duration was grouped into five categories: ≤5 (short sleepers), 6, 7 (reference), 8, and ≥9 h (long sleepers). We identified all cases with incident dementia, diagnosed using DSM‐IV criteria. Results: Three thousand two hundred eighty six participants with baseline information about sleep duration had a median duration of follow‐up of 3.2 years. There were 140 incident cases of dementia. The relative risks (RR) for short sleepers and for long sleepers were 2.36 (95% CI = 1.07–5.21, P = 0.03) and 2.40 (95% CI = 1.20–4.81, P = 0.01), respectively. After adjustment for potential confounders, the RR was only marginally increased for short sleepers (1.87, 95% CI = 0.85–4.15, P = 0.12) but remained increased for long sleepers (2.18; 95% CI = 1.09–4.37, P = 0.03). Conclusions: Prolonged sleep duration (night‐time sleep and daytime napping) may be associated with an increased risk of dementia.