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Bilateral cerebral hemispheric infarction associated with sildenafil citrate (Viagra ® ) use
Author(s) -
Kim K.K.,
Kim D. G.,
Ku Y. H.,
Lee Y. J.,
Kim W.C.,
Kim O. J.,
Kim H. S.
Publication year - 2008
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2007.02025.x
Subject(s) - sildenafil , medicine , hemiparesis , cerebral infarction , erectile dysfunction , cardiology , infarction , middle cerebral artery , anesthesia , angiography , myocardial infarction , ischemia
Sildenafil citrate (Viagra ® ) is one of the frequently prescribed drugs for men with erectile dysfunction. We describe a 52‐year‐old man with bilateral middle cerebral artery (MCA) territory infarction after sildenafil use. He ingested 100 mg of sildenafil and about 1 h later, he complained of chest discomfort, palpitation and dizziness followed by mental obtundation, global aphasia and left hemiparesis. Brain magnetic resonance imaging documented acute bilateral hemispheric infarction, and cerebral angiography showed occluded bilateral MCA. Despite significant bilateral MCA stenosis and cerebral infarction, systemic hypotension persisted for a day. We presume that cerebral infarction was caused by cardioembolism with sildenafil use.