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Vincristine‐induced acute neurotoxicity versus Guillain–Barré syndrome: a diagnostic dilemma
Author(s) -
González Pérez P.,
SerranoPozo A.,
FrancoMacías E.,
MontesLatorre E.,
GómezAranda F.,
Campos T.
Publication year - 2007
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2007.01842.x
Subject(s) - medicine , guillain barre syndrome , neurotoxicity , vincristine , fulminant , polyradiculoneuropathy , anesthesia , pediatrics , chemotherapy , toxicity , cyclophosphamide
We report the case of a patient with acute lymphoblastic leukaemia who, after the initiation of treatment with vincristine (VCR), developed a fulminant motor polyradiculoneuropathy resembling an axonal variant of Guillain‐Barré syndrome (GBS). This report shows that differentiating between axonal GBS and VCR‐induced acute neurotoxicity may be a challenge for clinicians.