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Eye movement disorders in vitamin B12 deficiency: two new cases and a review of the literature
Author(s) -
Akdal G.,
Yener G. G.,
Ada E.,
Halmagyi G. M.
Publication year - 2007
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2007.01824.x
Subject(s) - medicine , vitamin b12 , eye movement , movement disorders , nystagmus , pediatrics , audiology , physical medicine and rehabilitation , ophthalmology , disease
Eye movement disorders are rarely reported in vitamin B12 deficiency. We describe two cases with eye movement disorder and vitamin B12 deficiency; one with bilateral internuclear ophthalmoplegia and the other with downbeat nystagmus. Both of the patients received replacement therapy but their eye movement disorders did not respond to treatment. We also review the nine previously reported cases.