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Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA)
Author(s) -
Sharma V. K.,
Tsivgoulis G.,
Lao A. Y.,
Flaster M.,
Frey J. L.,
Malkoff M. D.,
Alexandrov A. V.
Publication year - 2007
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2006.01654.x
Subject(s) - medicine , thrombolysis , tissue plasminogen activator , occlusion , cardiology , common carotid artery , stroke (engine) , internal carotid artery , fibrinolytic agent , carotid arteries , myocardial infarction , mechanical engineering , engineering
Although common carotid artery (CCA) occlusions are rare, acute clinical presentations vary from mild to devastating strokes primarily due to tandem occlusions in the intracranial arteries. Three patients with acute CCA occlusions were treated with systemic tissue plasminogen activator (TPA). Blood pressures were kept at the upper limits allowed with TPA therapy with fluid balance and the ‘head‐down’ position. Recanalization occurred in intracranial vessels only. Marked early neurological improvement occurred in two of three patients. CCA occlusions should not be considered contra‐indication to systemic thrombolysis.