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Modern Neurosurgery Clinical Translation of Neuroscience Advances
Author(s) -
Jellinger K. A.
Publication year - 2005
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2005.01125.x
Subject(s) - citation , medicine , clinical neuroscience , neurosurgery , library science , neuroscience , computer science , psychology , psychiatry , neurology
This book contains information obtained from authentic and highly regarded sources. Reprinted material is quoted with permission, and sources are indicated. A wide variety of references are listed. Reasonable efforts have been made to publish reliable data and information, but the authors and the publisher cannot assume responsibility for the validity of all materials or for the consequences of their use. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage or retrieval system, without prior permission in writing from the publisher. The fee code for users of the Transactional Reporting Service is ISBN 0-8493-1482-8/05/$0.00+$1.50. The fee is subject to change without notice. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. The consent of CRC Press LLC does not extend to copying for general distribution, for promotion, for creating new works, or for resale. Specific permission must be obtained in writing from CRC Press LLC for such copying. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation, without intent to infringe. Modern neurosurgery : clinical translation of neuroscience advances / edited by Dennis A. Turner. p. cm.-(Frontiers in neuroscience) Includes bibliographical references and index. Advances in clinical neuroscience often arise from a better understanding of brain function and hypotheses based at the cellular, system, or organ level. Recent emphasis is on translating functions or structure-based hypotheses into clinical treatment schemes. This process of translational research depends on a number of critical steps, and in most cases, a clinical market that would make commercialization worthwhile financially. Rather than focus on current treatment schemes, this volume will critically discuss treatments in the process of development, particularly those that have arisen or will arise from advances in neuroscience knowledge. The three categories of such treatments are: (1) treatments, aids, and techniques currently in clinical trials or pending U.S. Food and Drug Administration (FDA) approval and new indications for older approved drugs and devices; (2) advances in the promising preclinical stages that may lead to a rapid progression to initial human trials over the next 5 to 10 years; and (3) approaches that failed at the clinical application level, but still offer insights into whether the initial hypothesis was invalid …