Premium
Long‐term effect of bone marrow transplantation in adult‐onset adrenoleukodystrophy
Author(s) -
Hitomi T.,
Mezaki T.,
Tomimoto H.,
Ikeda A.,
Shimohama S.,
Okazaki T.,
Uchiyama T.,
Shibasaki H.
Publication year - 2005
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2005.01055.x
Subject(s) - medicine , adrenoleukodystrophy , bone marrow transplantation , motor function , transplantation , transcranial magnetic stimulation , bone marrow , pediatrics , surgery , stimulation , physical medicine and rehabilitation , peroxisome , receptor
We report a long‐term outcome of motor function in a patient with adult‐onset adrenoleukodystrophy after bone marrow transplantation (BMT). Clinically motor function gradually improved and became almost normal in 2 years after BMT. Serial transcranial magnetic stimulation showed gradual improvement of central motor conduction until 1 year after BMT, and then it became stable. Central motor conduction time and motor threshold were useful for monitoring the central motor function in this patient.