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Differences between hypertensive and non‐hypertensive ischemic stroke
Author(s) -
Arboix A.,
Roig H.,
Rossich R.,
Martínez E. M.,
GarcíaEroles L.
Publication year - 2004
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.2004.00910.x
Subject(s) - medicine , cardiology , stroke (engine) , hyperlipidemia , diabetes mellitus , cerebral infarction , infarction , risk factor , disease , hypertensive heart disease , myocardial infarction , ischemia , heart failure , mechanical engineering , engineering , endocrinology
We compared risk factors, clinical features, neuroimaging data, and outcome between hypertensive and non‐hypertensive ischemic stroke patients. Differential features of ischemic stroke patients with hypertension ( n = 768) and without hypertension ( n = 705) were assessed by bivariate analysis. Independent predictors of hypertensive ischemic stroke were determined by multivariate analysis. Atherothrombotic infarction and lacunar infarct were significantly more common in the hypertensive group, in which older age and a higher occurrence of previous cerebral infarction, hyperlipidemia, acute stroke onset, lacunar syndrome, and pons topography was also observed. Age of 85 years or older, valvular heart disease, and decreased consciousness were more common in non‐hypertensive patients. After multivariate analysis, lacunar syndrome, female gender, and previous infarction were directly associated with hypertensive ischemic stroke. Age of 85 years or older and valvular heart disease were inversely associated with hypertensive ischemic stroke. Hypertension was the main cardiovascular risk factor only for lacunes and atherothrombotic infarction, that is, ischemic stroke associated with small‐ and large‐artery disease.