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Event‐related brain potentials in paroxysmal kinesigenic choreoathetosis
Author(s) -
Münte T.F.,
Johannes S.
Publication year - 1996
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.1996.tb00239.x
Subject(s) - medicine , choreoathetosis , audiology , contingent negative variation , oddball paradigm , neuroscience , event related potential , stimulus (psychology) , electroencephalography , psychology , cognitive psychology , psychiatry , dystonia
Event‐related brain potentials (ERPs) were recorded in a 30 year old female patient with familial kinesigenic choreoathetosis and a group of control subjects. In line with previous observations the patient exhibited an enhanced amplitude of the early component of the contingent negative variation of the ERP in a two stimulus paradigm. Moreover, a greatly enhanced P3 amplitude was found in auditory and visual classification (oddball) paradigms. These results suggest a general upregulation of widespread subcortical projection systems leading to both, abnormal movements and abnormally high amplitudes of ERPs.