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Myasthenia gravis and chronic inflammatory demyelinating polyneuropathy
Author(s) -
Sempere A.P.,
Claveria L.E.,
CruzMartinez A.,
Duarte J.
Publication year - 1996
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.1996.tb00237.x
Subject(s) - chronic inflammatory demyelinating polyneuropathy , medicine , myasthenia gravis , prednisone , azathioprine , polyneuropathy , polyradiculoneuropathy , immunology , guillain barre syndrome , antibody , disease
We describe a patient with the previously unreported association of chronic inflammatory demyelinating polyneuropathy (CIDP) and myasthenia gravis (MG). Immunosuppressive treatment with azathioprine and prednisone achieved clinical and electrophysiological remission of MG and improvement of CIDP. As ophthalmoplegia occurs infrequently in CIDP, the possibility of MG should be considered when this sign is present in a patient with CIDP. Since current therapy with corticosteroids, plasma exchange and other immunomodulating agents is effective against both diseases, their association may be undereported.