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Everyday memory impairment, neuroradiological findings and physical disability in multiple sclerosis
Author(s) -
Haupts M.,
Calabrese P.,
Babinsky R.,
Markowitsch H.J.,
Gehlen W.
Publication year - 1994
Publication title -
european journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 124
eISSN - 1468-1331
pISSN - 1351-5101
DOI - 10.1111/j.1468-1331.1994.tb00065.x
Subject(s) - multiple sclerosis , medicine , recall , audiology , lesion , memory impairment , cognition , cohort , cognitive impairment , physical medicine and rehabilitation , psychology , psychiatry , cognitive psychology
Thirty‐five multiple sclerosis (MS) patients diagnosed according to the Poser criteria were examined in a variety of cognition and memory tasks. Their performance was compared to age‐ and gender‐matched healthy individuals. While there was no difference in overall intellectual performance and short‐term memory between the MS group and control subjects, the patient group showed significant deficits in several everyday memory tasks including story recall, object and face recognition, procedural, topographical and prospective memory tasks. An intra‐group comparison in the MS cohort revealed that those patients with a chronic‐progressive MS course exhibited the most substantial everyday memory impairments and highest EDSS scores. These findings coincide with the neuroradiological, semiquantitative lesion analysis which was also performed. In this analysis, the latter MS subgroup also had the highest lesion score, as a sign of an overall brain involvement