Premium
Total hip arthroplasty in HIV ‐infected patients: a retrospective, controlled study
Author(s) -
Tornero E,
García S,
Larrousse M,
Gallart X,
Bori G,
Riba J,
Rios J,
Gatell JM,
Martinez E
Publication year - 2012
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/j.1468-1293.2012.01017.x
Subject(s) - medicine , human immunodeficiency virus (hiv) , total hip arthroplasty , surgery , orthopedic surgery , arthroplasty , femoral head , retrospective cohort study , immunology
Background Although HIV ‐infected patients are at greater risk of presenting with ischaemic necrosis of the femoral head, there have been concerns about whether total hip arthroplasty ( THA ) may have worse outcomes than expected. Methods From the O rthopedic and T rauma S urgery database we identified all patients who had undergone THA because of ischaemic necrosis of the femoral head from J anuary 2001 until M arch 2010. Patient's diagnosis of HIV infection was confirmed at the time of arthroplasty by cross‐matching with the HIV unit database. For every THA in HIV ‐infected patients, two THA s in patients not known to be HIV ‐infected, with the same diagnosis of ischaemic necrosis of the femoral head and having undergone surgery over the same period, were randomly selected. THA s were compared in HIV ‐ and non‐ HIV ‐infected patients for surgical procedure, in‐patient stay and long‐term prognosis. Results There were 18 THA s in 13 HIV ‐infected patients and 36 THA s in 27 non‐ HIV ‐infected patients. No significant differences were observed in the mean time spent in surgery (106 vs. 109 minutes, respectively; P = 0.66), the need for red cell transfusion (1 vs. 4, respectively; P = 0.48) or the mean duration of hospitalization (7.8 vs. 9.4 days, respectively; P = 0.48). The two groups showed similar postoperative functional results, which were maintained until the end of the follow‐up period (median 3.3 years in the HIV‐positive group and 5.8 years in the HIV‐negative group). Conclusion Our study suggests that the outcome of THA in HIV ‐positive patients is not worse than that of HIV ‐negative patients, although future research on larger numbers of patients is required to confirm this.