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Abnormal thyroid function in older men with or at risk for HIV infection *
Author(s) -
Wiener M,
Lo Y,
Klein RS
Publication year - 2008
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/j.1468-1293.2008.00601.x
Subject(s) - medicine , subclinical infection , overweight , thyroid function , body mass index , thyroid stimulating hormone , thyroid , thyroid function tests , hepatitis c , hormone , cross sectional study , pathology
Objectives The aim of the study was to evaluate the prevalence of and factors associated with abnormal thyroid function in older men with or at risk for HIV infection. Methods A cross‐sectional analysis of 636 men ≥49 years old was carried out using data obtained from interviews, from measurements of body mass index (BMI), HIV‐1 serology and viral load, CD4 cell count, hepatitis C virus (HCV) assays, thyroid‐stimulating hormone (TSH) and free thyroid hormone levels. Results Participants were 54% black, 57% overweight/obese, 57% HIV seropositive, and 72% HCV seropositive; 38% reported recent cocaine or heroin use. Decreased TSH was found in 56 men (8.8%) and raised TSH in 23 men (3.6%). Only three men had abnormal free thyroxine levels. Conclusions Abnormal TSH levels were noted in 12.4% of older men with or at risk for HIV infection, but nearly all reflected subclinical hyperthyroidism or subclinical hypothyroidism.