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Vanishing bile duct syndrome in a patient with advanced AIDS
Author(s) -
Hindupur S,
Yeung M,
Shroff P,
Fritz J,
Kirmani N
Publication year - 2007
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/j.1468-1293.2007.00415.x
Subject(s) - medicine , cholestasis , magnetic resonance cholangiopancreatography , immunosuppression , endoscopic retrograde cholangiopancreatography , jaundice , gastroenterology , liver biopsy , bile duct , biopsy , pancreatitis
A 39‐year‐old HIV‐infected woman developed signs and symptoms of obstructive jaundice and cholestasis. Serological tests were positive for cytomegalovirus (CMV) infection. There was no evidence of AIDS cholangiopathy in ultrasonography or magnetic resonance cholangiopancreatography (MRCP). A liver biopsy revealed marked ductopenia and the patient was diagnosed with vanishing bile duct syndrome, thought to be secondary to CMV infection as a result of profound immunosuppression. To the best of our knowledge, this is the first reported case of vanishing bile duct syndrome diagnosed in a patient with HIV/AIDS.