Premium
Characteristics of patients diagnosed with AIDS shortly after first detection of HIV antibodies in Lyon University hospitals from 1985 to 2001 *
Author(s) -
Baratin D,
Marceillac E,
Trepo C,
Cotte L,
Peyramond D,
Chidiac C,
Touraine JL,
Livrozet JM,
Fabry J,
Allard R,
Vanhems P
Publication year - 2004
Publication title -
hiv medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.53
H-Index - 79
eISSN - 1468-1293
pISSN - 1464-2662
DOI - 10.1111/j.1468-1293.2004.00220.x
Subject(s) - medicine , confidence interval , odds ratio , heterosexuality , pneumonia , pneumocystis carinii , pediatrics , opportunistic infection , human immunodeficiency virus (hiv) , viral disease , immunology , homosexuality , pneumocystis jirovecii , gender studies , sociology
Summary A diagnosis of AIDS shortly after the detection of HIV antibodies suggests a long‐lasting course of the disease without care. The factors associated with a short delay between the initial HIV‐1‐positive test and the first AIDS‐defining event were identified in 1901 patients from 1985 to 2001 in Lyon University hospitals. A total of 576 individuals (30.3%) had an interval of ≤3 months between the detection of HIV infection and AIDS. The factors independently associated with a delay of ≤3 months were: age from 30 to 44 years [odds ratio (OR) 2.5; 95% confidence interval (CI) 1.9–3.2]; age from 45 to 59 years (OR 5.6; 95% CI 3.9–7.8); age ≥60 years (OR 4.5; 95% CI 2.5–8.1), compared to those<30 years old; heterosexuality (OR 2.4; 95% CI 1.6–3.4); injection drug use (OR 2.1; 95% CI 1.5–2.7); and other exposures (OR 2.4; 95% CI 1.6–3.4), compared to homosexual exposure; two opportunistic infections at AIDS (OR 1.8; 95% CI 1.4–2.4) compared to one; and Pneumocystis carinii pneumonia as initial AIDS event (OR 2.6; 95% CI 1.8–3.7), compared to Kaposi's sarcoma. These results provide opportunities to refocus local public health interventions to reduce delayed access to care.