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Nanosystems for skin hydration: a comparative study
Author(s) -
Esposito E.,
Drechsler M.,
Mariani P.,
Sivieri E.,
Bozzini R.,
Montesi L.,
Menegatti E.,
Cortesi R.
Publication year - 2007
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.2007.00362.x
Subject(s) - liposome , nanotechnology , nanoparticle , colloid , materials science , scanning electron microscope , dynamic light scattering , chemistry , chemical engineering , organic chemistry , composite material , engineering
Synopsis The present investigation describes a comparative study for the design of innovative topical formulation for skin hydration. In particular, different colloidal forms based on lipidic components have been produced and characterized. Morphology and dimensional distribution have been investigated by means of electron microscopy and photon correlation spectroscopy. Nanoparticulate systems characterized by different morphology and dimensions depending on production procedures have been obtained, namely cubosomes, nanovesicles, solid lipid nanoparticles and liposomes. Hydration power has been studied by means of a corneometer, measuring the skin electrical capacitance before and after the application of opportunely viscosized nanoparticulate systems. It has been demonstrated that nanovesicle gel displayed a pronounced hydration power with respect to the other nanostructured forms, its hydration effect on skin was 3.5‐fold higher, with respect to the untreated area, after 5 min from the application and 1.5‐fold higher after 2 h.