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Ability of moisturizers to reduce dry skin and irritation and to prevent their return
Author(s) -
Simion F. A.,
Abrutyn E. S.,
Draelos Z. D.
Publication year - 2006
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.2006.00314_4.x
Subject(s) - dry skin , skin irritation , irritation , medicine , dermatology , dry cough , immunology
Presented in part at the 58th Annual Meeting of the American Academy of Dermatology, 2000, and at the Annual Scientific Meeting of the Society of Cosmetic Chemists, December 2000 Assays of moisturizer efficacy have traditionally focused on a moisturizer's ability to alleviate dry skin. More recently, a moisturizer's ability to prevent primary irritation has been recognized. To assess and compare the ability of moisturizers to alleviate skin dryness and primary irritation, as well as prevent their return, four controlled‐application clinical ( in vivo ) studies were carried out: hand‐wash test, regression test, reduction in pre‐existing irritation study, and prevention‐of‐irritation studies. Overall conclusions were confirmed in a home‐use clinical (validation) study of people suffering from mild eczema. The controlled in vivo studies demonstrate that: (a) a moisturizer can alleviate skin dryness and irritation, and prevent their return; and (b) the efficacy of different moisturizers can be differentiated, based on their composition. The home‐use study results demonstrated that the most effective moisturizer identified by the controlled‐application studies was highly effective against the signs of eczema. In vivo modelling of moisturizer efficacy enables assessment and optimization of different benefits separately, while predicting the quantitative and perceived (observed) relevance of the benefits the moisturizer delivers to consumers.