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Comparative study of the physiological properties of collagen, gelatin and collagen hydrolysate as cosmetic materials
Author(s) -
Li G. Y.,
Fukunaga S.,
Takenouchi K.,
Nakamura F.
Publication year - 2005
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.2004.00251.x
Subject(s) - gelatin , hydrolysate , keratinocyte , chemistry , adhesion , cell growth , cell adhesion , biochemistry , cell , in vitro , hydrolysis , organic chemistry
Synopsis The cell biological properties of collagen, gelatin and collagen hydrolysate (<15 000 Da) were studied using murine keratinocytes. Keratinocyte culture experiments demonstrated that only collagen had significant effects on cell attachment and proliferation, but the results of cells cultured on gelatin and collagen hydrolysate showed the rates of adhesion and proliferation were similar to those of cells cultured on plastic as a control. It is concluded that collagen has better physiological effects than those of gelatin and collagen hydrolysate as skin‐care cosmetic materials.