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Repair of dry skin by minerals in seawater: OLIGOMARINE ® as a skin moisturizer
Author(s) -
Ooe M.,
Okumura H.,
Yamamura T.,
Matsunaka H.,
Morioka T.
Publication year - 2004
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.2004.00242_4.x
Subject(s) - involucrin , stratum corneum , moisturizer , chemistry , dry skin , corneocyte , human skin , keratinocyte , seawater , lotion , barrier function , biochemistry , microbiology and biotechnology , biology , dermatology , in vitro , medicine , organic chemistry , ecology , genetics
OLIGOMARINE ® is a complex of minerals obtained from seawater. In a cell culture system, OLIGOMARINE ® stimulated not only the cell activation but also the collagen synthesis of fibroblasts. In addition, OLIGOMARINE ® might have accelerated the keratinization as the expression of suprabasal markers, such as involucrin and transglutaminase, were promoted in cultured normal human keratinocytes. Furthermore, the water‐holding properties and permeability barrier function of the stratum corneum were enhanced by using lotion containing OLIGOMARINE ® . These results suggested that OLIGOMARINE ® would be useful as a humectant for the prevention or improvement of dry skin.