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Enhanced substantivity of hyaluronic acid on keratin substrates via polymer complexation
Author(s) -
PAVLICHKO J.P.,
GODDARD E.D.,
BAND P.A.,
LESCHINER A.
Publication year - 1994
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.1994.tb00099.x
Subject(s) - hyaluronic acid , cationic polymerization , chemistry , keratin , polymer , zeta potential , cellulose , glycosaminoglycan , electrokinetic phenomena , polymer chemistry , biophysics , organic chemistry , biochemistry , chemical engineering , anatomy , medicine , pathology , biology , nanoparticle , engineering
Synopsis Complexes of glycosaminoglycans and certain cationic polymers have been identified which provide utility in skin and hair care applications. The combination of biologically engineered hyaluronic acid and the cationic cellulose polymer, polyquaternium‐10, results in a unique, stable, multifunctional, association complex with enhanced polymer functionality. Complexation of the anionic and cationic polysaccharide polymers renders hyaluronic acid substantive to keratin, as evidenced by zeta potential changes of the surface charge of hair via electrokinetic streaming potential measurements. Radiolabelling techniques show as much as a ten‐fold increase in bound hyaluronic acid on hair after water rinsing. The resulting ‘enhanced’substantivity of hyaluronic acid, as part of the complex, thus extends the time hyaluronic acid remains in contact with keratinous surfaces, prolonging its humectant, moisturizing and skin‐smoothening effects.