Premium
In‐use tolerability of two new syndet bars with sodium cocoyl isethionate, disodium lauryl sulfosuccinate and wheat starch as major ingredients in differing relations: results of a cross‐over trial
Author(s) -
KORTING H.C.,
LUKACS A.,
HAMM D.,
STANZL K.,
BRAUNFALCO O.
Publication year - 1992
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.1992.tb00060.x
Subject(s) - tolerability , erythema , chemistry , starch , wheat starch , sodium , food science , pharmacology , medicine , dermatology , adverse effect , organic chemistry
Synopsis In a cross‐over trial two different new syndet bars differing in their content of sodium cocoyl isethionate, disodium lauryl sulfosuccinate and wheat starch as major components were compared in the cleansing of hand skin of 72 healthy volunteers. The preparation designated ‘T’containing a higher amount of wheat starch turned out to be less irritant as judged from the parameters itching and erythema (p < 0.05, Wilcoxon's test for matched pairs). The present trial design looks appropriate to differentiate the irritancy potential of two chemically similar syndet bar preparations.