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Evolution of lipid composition in skin treated with blackcurrant seed oil
Author(s) -
BROD J.,
TRAITLER H.,
STUDER A.,
LACHARRIERE O.
Publication year - 1988
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.1988.tb00014.x
Subject(s) - stratum corneum , chemistry , linoleic acid , food science , fatty acid , dry weight , emulsion , linolenic acid , dry skin , human skin , biochemistry , stearic acid , botany , biology , organic chemistry , dermatology , medicine , genetics
Synopsis This report utilizes a new procedure based on epidermal stripping to analyse unlabelled skin fatty acids. This technique was applied to the study of human dry skin treated with blackcurrant seed oil, an essential fatty acid rich lipid also containing γ linolenic acid. In human dry skin the usual fatty acids were found in the stratum corneum as in normal skin outer layers. Among the saturated series no significant difference was observed in the C16 chain but a smaller quantity of C18:0 was detected. In the unsaturated series a marked fall of linoleic acid as well as a higher level of C16:1 in the stratum corneum appeared as the major significant events that could characterize dry skin. γ linolenic acid was detectable neither in normal nor in dry skin. α linolenic acid was found but not consistently. After multiple applications of blackcurrant seed oil in an emulsion preparation, impregnation of the stratum corneum was complete, and essential or other fatty acids contained in the oil (particularly linoleic and linolenic acids) were found in combination with endogenous lipids. Possibly they contribute to enhance the protective effect of the stratum corneum.