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Permeability characteristics of the human nail plate
Author(s) -
WALTERS K. A.,
FLYNN G. L.
Publication year - 1983
Publication title -
international journal of cosmetic science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.532
H-Index - 62
eISSN - 1468-2494
pISSN - 0142-5463
DOI - 10.1111/j.1467-2494.1983.tb00348.x
Subject(s) - nail plate , stratum corneum , nail (fastener) , permeability (electromagnetism) , penetration (warfare) , context (archaeology) , permeation , dermatology , materials science , medicine , chemistry , geology , engineering , pathology , operations research , paleontology , biochemistry , membrane , metallurgy , psoriasis
Synopsis The permeation of chemicals across the nail plate and their consequent effects are discussed in relation to cosmetic toxicity and possible clinical efficacy. The reviewed data are then assessed and placed in context with recent observations on the direct assessment of permeability of the human nail plate. Although marked differences between the diffusional barrier characteristics of nail and stratum corneum are shown, a reasonably unified picture of nail plate permeability is drawn from the collective observations. The cosmetic and clinical implications of chemical penetration of the nail plate are briefly outlined and places where knowledge needs to be strengthened are identified. La perméabilité de l'ongie humain