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Hormones and drinking behaviour: New findings on ghrelin, insulin, leptin and volume‐regulating hormones. An ESBRA Symposium report
Author(s) -
ADDOLORATO GIOVANNI,
LEGGIO LORENZO,
HILLEMACHER THOMAS,
KRAUS THOMAS,
JERLHAG ELISABET,
BLEICH STEFAN
Publication year - 2009
Publication title -
drug and alcohol review
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.018
H-Index - 74
eISSN - 1465-3362
pISSN - 0959-5236
DOI - 10.1111/j.1465-3362.2008.00023.x
Subject(s) - ghrelin , hormone , leptin , craving , appetite , insulin , medicine , peptide hormone , endocrinology , psychology , addiction , obesity , neuroscience
There is growing evidence for a role of appetite‐related peptides and volume‐regulating hormones in alcoholism. In particular, recent evidence has suggested that hormones, such as ghrelin, insulin and leptin and volume‐regulating hormones, could play a role in alcohol‐seeking behaviour. The goal of this review is to discuss the results of recent preclinical and clinical investigations on this topic. The findings indicate that neuroendocrinological mechanisms are potentially involved in the neurobiology of alcohol craving. Accordingly, research on this topic could lead to possible development of new therapeutic approaches in the treatment of patients with alcohol problems. [Addolorato G, Leggio L, Hillemacher T, Kraus T, Jerlhag E, Bleich S. Hormones and drinking behaviour: New findings on ghrelin, insulin, leptin and volume‐regulating hormones. An ESBRA Symposium report. Drug Alcohol Rev 2009]