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Trends in Type 1 diabetes incidence in the UK in 0‐ to 14‐year‐olds and in 15‐ to 34‐year‐olds, 1991–2008
Author(s) -
Imkampe A.K.,
Gulliford M. C.
Publication year - 2011
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.2011.03288.x
Subject(s) - medicine , incidence (geometry) , poisson regression , demography , type 1 diabetes , diabetes mellitus , type 2 diabetes , pediatrics , young adult , gerontology , endocrinology , environmental health , population , physics , sociology , optics
Diabet. Med. 28, 811–814 (2011) Abstract Aim To describe Type 1 diabetes incidence trends in the UK between 1991 and 2008 in children aged 0–14 years and in young adults aged 15–34 years. Methods Data from the UK General Practice Research Database were analysed, including 3002 individuals (1565 aged 0–14 years and 1437 aged 15–34 years) newly diagnosed with Type 1 diabetes. Poisson regression was used to model annual incidence increases and seasonality effects. Results Type 1 diabetes incidence increased from 11 to 24/100 000 person‐years in boys and from 15 to 20/100 000 person‐years in girls. In adults, the incidence rate increased from 13 to 20/100 000 person‐years (men) and from 7 to 10/100 000 person‐years (women). Annual incidence increases tended to be greater in children (4.1%, 95% CI 3.0–5.2%) compared with 15‐ to 34‐year‐olds (2.8%, 95% CI 1.6–3.9%). There was evidence of higher incidence rates during autumn and winter in children, but not in adults. Conclusions A continuing increase in Type 1 diabetes incidence was shown that was greater in children than in young adults. Seasonal variation was observed in children only.