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Impact of personalized cardiovascular disease risk estimates on physical activity—a randomized controlled trial
Author(s) -
Price H. C.,
Griffin S. J.,
Holman R. R.
Publication year - 2011
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.2010.03212.x
Subject(s) - medicine , diabetes mellitus , randomized controlled trial , physical activity , physical therapy , disease , risk assessment , endocrinology , computer security , computer science
Diabet. Med. 28, 363–372 (2011) Abstract Aim  Informing a person of their individual risk of developing a disease in the future may be sufficient to provide the person with the impetus to adopt risk reducing behaviours. The aim of this study was to determine if a personalised 10‐year cardiovascular disease (CVD) risk estimate can increase physical activity and other risk reduction behaviours in adults at high risk of CVD. Methods  Pilot 2 × 2 factorial randomised controlled trial conducted in Oxfordshire, UK including 194 adults at increased CVD risk (10‐year CVD risk ≥20%) recruited from four general practices. Main outcome measure at one month was physical activity measured by accelerometer. Results  Median (IQR) age was 62.3 (54.9, 66.1) years, 67% were men and 19% had known diabetes. Mean (SD) total accelerometer counts per day was 297 × 10 −3 (110 × 10 −3 ) and activity of moderate or greater intensity was undertaken for 53 (22) minutes per day. In the 185 (95%) participants attending follow‐up an increase in physical activity was not seen. There was a non‐significant 0.5% (p = 0.56) greater increase in accelerometer counts in those receiving personalised CVD risk estimates. No significant within or between group changes were seen at one month in estimated 10‐year CVD risk. A net 7% decrease in mean LDL cholesterol (p = 0.004) was seen in the intervention group despite similar increases in new prescriptions for lipid lowering therapies. Conclusion  In adults at increased risk of CVD provision of personalised 10‐year CVD risk estimates did not appear to increase physical activity or estimated CVD risk over a one‐month period.

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