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Prevalence and risk factors for asymptomatic bacteriuria in women with Type 2 diabetes mellitus
Author(s) -
Ishay A.,
Lavi I.,
Luboshitzky R.
Publication year - 2006
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.2005.01758.x
Subject(s) - medicine , asymptomatic bacteriuria , asymptomatic , diabetes mellitus , type 2 diabetes , type 2 diabetes mellitus , risk factor , bacteriuria , endocrinology , urine
Aims Asymptomatic bacteriuria (ASB) has been considered as a complication in diabetic women. The reported data on the prevalence and various risk factors for ASB appear to be conflicting. Consequently, we investigated the prevalence and major risk factors of ASB in women with Type 2 diabetes mellitus. Methods A total of 411 non‐pregnant women (aged 59.6 ± 10.8 years) with Type 2 diabetes, and 160 women without diabetes (aged 53.3 ± 15.1 years) assigned as controls, attending an outpatient endocrine clinic in a university‐affiliated teaching hospital, were included. All participating women were interviewed and screened for the presence of ASB. In all participants, fasting blood glucose, HbA 1c and renal function were measured. Complications of diabetes were also assessed. Results Of the 411 diabetic women, 25 (6.1%) had ASB, compared with four of 160 (2.5%) in control women ( P = 0.07). Independent risk factors for the presence of ASB were albuminuria > 150 mg/24 h [odds ratio (OR) 4.96 (95% CI 1.64–15.0, P = 0.005)] and serum creatinine [OR 3.5 (95% CI 1.4–8.8, P = 0.008)]. No significant association was evident with age, BMI, duration of disease, glycaemic control assessed by HbA 1c or chronic complications of diabetes, namely macrovascular disease, neuropathy and retinopathy. Conclusions Women with Type 2 diabetes are not at higher risk of developing ASB than non‐diabetic women. Independent and significant risk factors for ASB are macroalbuminuria and serum creatinine. The low prevalence of ASB found in this study may be as a result of the ethnic origin of these women and the circumcised state of their partners.