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Sequelae of Acute Hypoglycaemia on 24 hour Blood Pressure and Metabolic Parameters in Normal and Type 1 (Insulin‐dependent) Diabetic Individuals
Author(s) -
Avogaro A.,
Crepaldi C.,
Miola M.,
Penzo M.,
Maran A.,
Zanin L.,
Rossi G. P.,
Moretti M.,
Palatini P.,
Tiengo A.
Publication year - 1994
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1994.tb02038.x
Subject(s) - medicine , insulin , endocrinology , blood pressure , diabetes mellitus , type 2 diabetes , type 1 diabetes , hypoglycemia
This study was performed to assess possible delayed after‐effects of acute hypoglycaemia on blood pressure (BP) and heart rate (HR) over a 24‐h period. Eleven insulin‐dependent diabetic patients and 11 sex, age, and body mass index matched non‐diabetic subjects were studied. Blood pressure was measured using a non‐invasive ambulatory blood pressure monitor following acutely induced hypoglycaemia in the morning. No significant differences were observed in 24‐h systolic and diastolic BP and HR in either groups, between the day when hypoglycaemia was induced and the day when plasma glucose was kept normal. In diabetic patients, hypoglycaemia induced a temporary but significant fall in mean BP (‐7 ± 1 mmHg vs ‐2 ± 2; p < 0.05). Plasma glucose levels were significantly higher in insulin‐dependent diabetic patients following hypoglycaemia than in those observed during the reference test. This study demonstrates that acute hypoglycaemia in insulin‐dependent diabetic subjects does not cause significant alterations in 24‐h BP in either diabetic or normal subjects.