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Is There a Role for Beta‐blockers in Hypertensive Diabetic Patients?
Author(s) -
Tse W.Y.,
Kendall M.
Publication year - 1994
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1994.tb02009.x
Subject(s) - medicine , beta (programming language) , diabetes mellitus , adrenergic beta antagonists , endocrinology , propranolol , computer science , programming language
Clinical trials have not yet produced long‐term primary prevention data on the effects of angiotensin converting enzyme inhibitors, calcium antagonists or alpha‐blockers on cardiovascular complications and sudden death in hypertensive patients. Large‐scale secondary preventive studies on calcium antagonists have been disappointing. In contrast, beta‐blockers have an established role in cardioprotection both in primary and secondary preventive studies and there is evidence to show that the cardioprotective effect of beta‐blockers is even greater in the diabetic population. Furthermore, this favourable impact of beta‐blockers was achieved despite diabetic patients having a worse risk factor profile and poorer prognosis. In this review the use of beta‐blockers in diabetic patients will be discussed and their impact on coronary artery disease described.