Premium
Influences on Weight Loss in Type 2 Diabetic Patients: Little Long‐term Benefit from Group Behaviour Therapy and Exercise Training
Author(s) -
Blonk M.C.,
Jacobs M.A.J.M.,
Biesheuvel E.H.E.,
WeedaMannak W.L.,
Heine R.J.
Publication year - 1994
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1994.tb00305.x
Subject(s) - medicine , weight loss , confidence interval , blood pressure , physical therapy , body weight , diabetes mellitus , obesity , zoology , endocrinology , biology
The aim of our study was to assess the long‐term (24 months) efficacy of a comprehensive weight reduction programme as compared to that of a conventional programme. The Comprehensive Programme comprised, besides the Conventional Programme (diet counselling), behavioural modification and exercise training. The 2‐year follow‐up period was completed by 53 patients (19M/34F; 88.3%). The differences (95% confidence intervals; CI) between the change in body weight of patients in the Comprehensive Programme compared to the Conventional Programme after 6 and 24 months of treatment were −2.2 (‐4.0, −0.3) kg, p = 0.03 and −1.3 (‐3.3, 0.7) kg, p = 0.21, respectively. In comparison to the Conventional Programme, the Comprehensive Programme resulted in a greater decrease (95% CI) of HbA 1c after 6 months: −0.8 (‐1.2, −0.2)%, p = 0.01, but not after 2 years: −0.4 (‐1.0, 0.1)%, p = 0.12. The effects on blood pressure and serum lipids of the Comprehensive Programme and the Conventional Programme were comparable. Changes in body weight at 6 months correlated well with changes in HbA 1c , fasting plasma insulin, and blood pressure, whereas at 24 months no such correlation was found with HbA 1c . Pretreatment variates that were associated with the greatest 2‐year weight loss were a high HbA 1c value, a low energy per cent carbohydrate intake and a low percentage of obese subjects within the family. In conclusion, the long‐term outcome of the Comprehensive Programme was not different from that of the Conventional Programme. The achieved body weight reduction was associated with a sustained fall in blood pressure, but with only a transient beneficial effect on the glycaemic control in the Type 2 diabetic patient.