Premium
Skin Epidermal Thickness and Vascular Density in Type 1 Diabetes
Author(s) -
Malik R. A.,
Metcalfe J.,
Sharma A. K.,
Day J. L.,
Rayman G.
Publication year - 1992
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1992.tb01773.x
Subject(s) - medicine , arteriole , diabetes mellitus , dorsum , venule , skin thickness , diabetic foot , type 2 diabetes , diabetic angiopathy , vascular disease , microcirculation , endocrinology , anatomy , dermatology
Epidermal skin thickness and vascular density were assessed in skin biopsies obtained from the dorsum of the foot in 28 Type 1 diabetic patients and 17 normal control subjects, matched for age. Epidermal skin thickness did not differ significantly between control subjects (74 ± 4 (± SE) μ m) and diabetic patients (78 ± 4 μm). It was not related to the duration of diabetes and presence of complications. Neither small (capillary) nor large (arteriole/venule) vessel densities differed significantly between control subjects (59 ± 6 mm −2 and 19 ± 2 mm −2 ) and diabetic patients (65 ± 4 mm −2 and 22 ± 3 mm −2 ). Vessel densities were unrelated to the duration of diabetes and presence of complications.