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Catecholamines and Blood Glucose Control in Type 1 Diabetes
Author(s) -
Bilo H. J. G.,
Gans R. O. B.,
Polee M. B.,
Maten J.,
PoppSnijders C.,
Donker A. J. M.
Publication year - 1991
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1991.tb02169.x
Subject(s) - medicine , endocrinology , catecholamine , diabetes mellitus , blood pressure , insulin , body mass index , type 2 diabetes , type 1 diabetes
To evaluate the influence of blood glucose control on serum catecholamine levels (which reflect both plasma and platelet levels), six healthy non‐diabetic subjects, seven well‐controlled Type 1 diabetic patients, and six poorly controlled Type 1 diabetic patients were studied before (baseline) and after standardized exercise. A significant correlation was found between serum noradrenaline and HbA 1 at baseline ( r = 0.53, p < 0.025) and after exercise ( r = 0.71, p < 0.001). Similar results were found for serum adrenaline ( r = 0.68, p < 0.005 and r = 0.61, p < 0.005, respectively) and consequently total serum catecholamine content ( r = 0.65, p < 0.005 and r = 0.75, p < 0.001, respectively). However, no relationship was found between serum catecholamine levels and actual blood glucose levels, age, body mass index or insulin dose. A moderate correlation was found between systolic blood pressure and serum levels of noradrenaline and total catecholamines after exercise ( r = 0.48 and r = 0.48, both p < 0.025).