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Diastolic Ventricular Function in Type 1 Diabetic Patients: A Study Using Doppler Echocardiography
Author(s) -
Grossmann G.,
Schmidt A.,
Hauner H.,
Göller V.,
Stauch M.,
Pfeiffer E.F.,
Hombach V.
Publication year - 1991
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1991.tb01573.x
Subject(s) - medicine , cardiology , diastole , heart failure , doppler echocardiography , diabetes mellitus , heart disease , diastolic function , heart rate , endocrinology , blood pressure
The transmitral flow velocity pattern of 28 Type 1 diabetic patients and 39 age‐matched healthy control subjects was studied for determination of left ventricular diastolic function. No patient had systemic hypertension, congestive heart failure, or ischaemic heart disease by clinical or electrocardiographic criteria. Echocardiographic measures of systolic ventricular function were within normal range in all subjects. The ratio of early to late transmitral peak flow velocity ( v e / v a ) was significantly decreased in the diabetic patients (1.3 ± 0.1 (± SE) vs 1.6 ± 0.1, p < 0.05), while other Doppler derived variables did not show any significant difference. No correlation of v e / v a with duration of diabetes was found ( r = −0.27), but it correlated with age in both groups (both r = −0.40, p < 0.05). Furthermore, a significant correlation was found between v e / v a and heart rate ( r = −0.55 for diabetic patients, p < 0.01; r = −0.58 for control subjects, p < 0.01). After matching for heart rate (24 diabetic patients and 24 control subjects) no significant decrease of v e / v a was observed in the diabetic group.