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Glucose Metabolism in a Patient with Insulinoma Complicated by Hyperosmolar Non‐ketotic State
Author(s) -
Ŝkrha J.,
Páv J.,
Svačina Ŝ.,
Ŝrámková J.,
Hilgertová J.
Publication year - 1990
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1990.tb01406.x
Subject(s) - medicine , insulinoma , hyperinsulinism , endocrinology , vomiting , carbohydrate metabolism , insulin , urinary system , metabolism , insulin resistance
A case of a patient with organic hyperinsulinism complicated by the development of hyperosmolar state is described. The hyperosmolar state was induced by vomiting and dehydration during an acute urinary tract infection. Impairment of glucose metabolism was confirmed by the finding of reduced tissue sensitivity to insulin during a euglycaemic clamp.