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Relationship Between Urinary Excretion of Sodium and Dopamine in Type 1 Diabetic Patients with and without Microalbuminuria
Author(s) -
Patrick A.W.,
Collier A.,
Clarke B.F.,
Jeffrey R.F.,
Lee M.R.
Publication year - 1990
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1990.tb01308.x
Subject(s) - microalbuminuria , medicine , endocrinology , excretion , dopamine , urinary system , type 2 diabetes , sodium , diabetes mellitus , chemistry , organic chemistry
The relationship between urinary sodium and dopamine excretion was investigated in 40 normal males and in 48 normotensive, Type 1 diabetic males, 11 with microalbuminuria and 37 with normal albumin excretion. In all three groups a significant correlation was demonstrated and the regression lines were similar. Thus, no evidence was found that a defect in dopamine mobilization contributes to the early renal pathophysiological changes of Type 1 diabetes.