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Pupillary Size in Children and Adolescents with Type 1 Diabetes
Author(s) -
Clarke C.F.,
Piesowicz A.T.,
Spathis G.S.
Publication year - 1989
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1989.tb01278.x
Subject(s) - medicine , diabetes mellitus , type 2 diabetes , pediatrics , endocrinology
Pupillary adaptation to darkness was studied in 63 children and adolescents with Type 1 diabetes using a simple portable pupillometer. Results were compared with those in a group of age‐related non‐diabetic children and expressed as the ratio of the pupil diameter to the iris diameter (pupil diameter %). In the diabetic patients the pupil diameter % was 61.1 ± 5.8 (44.4–71.9) % compared with 64.2 ± 4.1 (53.2–72.6) % in the control subjects ( p < 0.001). Abnormal pupillary adaptation to darkness was found more commonly than abnormal heart rate variation in response to a variety of stimuli in the diabetic patients. Pupillary adaptation to darkness may be useful as an indicator of subclinical autonomic neuropathy in diabetic children.