Premium
Type 2 Diabetes in Arab Patients in Kuwait
Author(s) -
Richens E. R.,
Abdella N.,
Jayyab A. K.,
AlSaffar M.,
Behbehani K.
Publication year - 1988
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1988.tb00975.x
Subject(s) - medicine , diabetes mellitus , family history , type 2 diabetes , disease , endocrinology
We describe the characteristics of 75 Arab Type 2 diabetic patients in Kuwait. Their age (± SD) at onset was 41 ± 10 years, and fasting serum C‐peptide concentration was 0.32 ± 0.23 nmol/l ( n =51). Fifty‐three percent (37/70) possessed HLA‐DR3 or ‐ DR4 epitopes, and 64% (47/73) had a family history of diabetes. Data review suggested that they could be segregated into two groups, those under 40 years old at onset (32 ± 6 years, n =37), and the remainder (48 ± 6 years, n =38) ( p <0.001). Those in the former group had a significantly higher frequency of a family history of diabetes than those in the latter group (92% vs 38%, p <0.001) suggestive of a greater genetic influence on the development of Type 2 diabetes in those with early onset disease.