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Diabetic Pregnancy following Renal Transplantation
Author(s) -
Grenfell A.,
Bewick M.,
Brudenell J. M.,
Carr J. V.,
Parsons V.,
Snowden S.,
Watkins P. J.
Publication year - 1986
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1986.tb00735.x
Subject(s) - medicine , pregnancy , transplantation , kidney transplantation , intensive care medicine , obstetrics , surgery , genetics , biology
Renal transplantation for diabetic nephropathy prolongs survival and the return of fertility makes pregnancy possible. We describe a successful pregnancy in a 38‐year‐old diabetic renal transplant recipient despite blindness, gangrenous toes, cardiac impairment, and both sensory and autonomic neuropathy. Renal function remained stable throughout the pregnancy which was complicated by supine hypertension, postural hypotension and increasing proteinuria. Fetal distress and increasing proteinuria precipitated delivery by Caesarian section at 29 weeks of a female infant weighing 1.1 kg. Following delivery, hypertension improved, gangrene resolved, proteinuria decreased, and renal function remained stable. Pregnancy in long‐standing diabetic patients with renal transplants, although hazardous, may be successful yet the maternal morbidity and mortality makes them inadvisable.