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Fasting Blood Glucose and Risk of Coronary Heart Disease, Stroke, and All‐cause Mortality: A 17‐year Follow‐up Study of Men Born in 1913
Author(s) -
Ohlson L.O.,
Svärdsudd K.,
Welin L.,
Eriksson H.,
Wilhelmsen L.,
Tibblin G.,
Larsson B.
Publication year - 1986
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1986.tb00702.x
Subject(s) - medicine , stroke (engine) , diabetes mellitus , myocardial infarction , incidence (geometry) , population , coronary heart disease , prospective cohort study , endocrinology , environmental health , mechanical engineering , physics , optics , engineering
This report concerns the relationship between baseline levels of fasting blood glucose (FBC) in non‐diabetics and the subsequent 17‐year incidence of coronary heart disease (CHD), stroke and all‐cause mortality. In 1963, 973 men aged 50 years were recruited from a general Swedish urban population for a prospective study of risk factors for CHD. Eight hundred and fifty‐five (88%) men agreed to participate and have been observed for 17 years. The 832 men who had no history of myocardial infarction, stroke, diabetes mellitus or who had a fasting blood glucose below 7.0 mmol/l at baseline were selected for this analysis. CHD occurred in 106 men, 35 developed a stroke and 137 died during follow‐up. When quintiles and deciles of the FBG distribution were considered, no trend of 17‐year incidence of CHD, stroke or death was apparent. However, for men with an FBG above the 95th percentile (>5.7 mmol/l) a non‐significant trend towards increasing risk was indicated.