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Systolic Time Intervals in Adolescents with Insulin‐dependent Diabetes Mellitus
Author(s) -
Northcote R. J.,
Semple C.,
Kesson C. M.,
Ballantyne D.
Publication year - 1985
Publication title -
diabetic medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.474
H-Index - 145
eISSN - 1464-5491
pISSN - 0742-3071
DOI - 10.1111/j.1464-5491.1985.tb00684.x
Subject(s) - medicine , cardiology , isometric exercise , contractility , diabetes mellitus , systole , ejection fraction , microangiopathy , heart failure , blood pressure , endocrinology , diastole
Systolic time intervals were used to evaluate left ventricular performance in 20 diabetic adolescents with a mean age of 15.2 ± 2.2 years (range 9–17 years) and were compared with an age‐ and sex‐matched control group. Pre‐ejection period index (PEPI), left ventricular ejection time index (LVET±l), total electromechanical systole index (QS 2 I) and the PEP to LVET ratio were calculated at rest and following sustained isometric handgrip (SIHG). None of the diabetics had demonstrable microangiopathy or autonomic neuropathy. There was no significant difference in resting or post‐exercise heart rate, PEPI, LVETI or PEP/LVET ratio between the two groups. QS 2 I was significantly prolonged ( p <0.05) at rest in the diabetics, but was not significantly different following SIHG. These results indicate that cardiac contractility is not detectably abnormal in young diabetics, compared to their adult counterparts who may develop impaired myocardial performance.