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Laparoendoscopic single‐site nephroureterectomy for upper urinary tract urothelial carcinoma: outcomes of an international multi‐institutional study of 101 patients
Author(s) -
Porpiglia Francesco,
Bertolo Riccardo
Publication year - 2013
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2013.11795.x
Subject(s) - urothelial carcinoma , medicine , upper urinary tract , urology , citation , library science , university hospital , general surgery , urinary system , cancer , computer science , bladder cancer
retrospective study involving >3000 patients from multiple European and US centres between 1992 and 2010. They include high-, midand low-volume institutes, as well as different populations. This helps to provide a heterogenous study cohort to better reflect the real clinical situation and hence to improve the reproducibility of the nomogram. The preoperative and postoperative models have a good predictive ability with a stratified C-index of 0.784 and 0.842, respectively, and the latter discriminates substantially better. The authors conclude that the Karakiewicz nomograms proved to have excellent accuracy and generalizability.