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Is mechanical bowel preparation in laparoscopic radical prostatectomy beneficial? An analysis of a J apanese national database
Author(s) -
Sugihara Toru,
Yasunaga Hideo,
Horiguchi Hiromasa,
Fujimura Tetsuya,
Nishimatsu Hiroaki,
Kume Haruki,
Ohe Kazuhiko,
Matsuda Shinya,
Fushimi Kiyohide,
Homma Yukio
Publication year - 2013
Publication title -
bju international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.773
H-Index - 148
eISSN - 1464-410X
pISSN - 1464-4096
DOI - 10.1111/j.1464-410x.2012.11725.x
Subject(s) - medicine , prostatectomy , laparoscopic radical prostatectomy , complication , incidence (geometry) , urology , multivariate analysis , body mass index , surgery , laparoscopic surgery , retrospective cohort study , laparoscopy , prostate cancer , cancer , physics , optics
What's known on the subject? and What does the study add? Recently, the ineffectiveness of bowel mechanical preparation prior to colorectal surgery was focused on. Although its effectiveness was widely accepted in laparoscopic prostatectomy, the data were limited. This retrospective multicentre study compared laparoscopic prostatectomy cases with and without bowel preparation and did not demonstrate the preparation's preferable effect in operation time and complication incidence, which suggested justification of the omission of bowel preparation.Objective To evaluate the effect of mechanical bowel preparation ( MBP ) prior to laparoscopic radical prostatectomy on peri‐operative outcomes.Patients and Methods Patients undergoing laparoscopic radical prostatectomy for T 1– T 2 tumours between 2008 and 2010 were identified in the J apanese D iagnosis P rocedure C ombination database. Patients were classified into a preoperative MBP group and a non‐ MBP group. The effects of MBP were evaluated by multivariate regression analysis of overall complication rate, operation time, postoperative length of stay ( PLOS ) and total costs with generalized estimating equations adjustment involving age, body mass index, C harlson score, hospital academic status and hospital volume.Results Comparing the 154 non‐ MBP and 580 MBP patients, overall complication rate, operation time, PLOS and total costs were 6.5% vs 6.9% ( P = 0.860), 222 vs 250 min ( P = 0.001), 11 vs 10 days ( P < 0.001) and 18 941 vs 19 015 US dollars ( P = 0.032), respectively. In the multivariate analyses, no significant differences were observed for the four outcomes ( P = 0.961, 0.194, 0.383 and 0.993, respectively). Complications were more frequently observed in older patients, and operation time tended to be longer in patients with higher body mass index and in hospitals with lower volumes. Longer PLOS and higher total costs were associated with older age, higher C harlson score and lower hospital volume.Conclusions We could not find any superiority of MBP on overall complications, operation time, PLOS and total costs in laparoscopic radical prostatectomy. The results support that MBP can be omitted prior to laparoscopic radical prostatectomy for T 1– T 2 prostate cancer.